CK7 expression in normal cells
biliary epithelial cells
CK7 expression in tumors
CK7 expression in tumors
-
cutaneous Paget disease (9500217, 9331290)
- Intraepidermal cytokeratin 7 expression is not restricted to Paget cells but is also seen in Toker cells and Merkel cells. (9989849)
mucinous cystadenocarcinoma of the breast
- All cases stain positively with cytokeratin 7 (CK7) but were negative with cytokeratin 20 (CK20).
papilary renal cell carcinoma
benign proliferative nipple duct lesions (10555003) See also
KRT19 (CK19)
References
Breast cancer and mammary lesions
Benign proliferative nipple duct lesions frequently contain CAM 5.2 and anti-cytokeratin 7 immunoreactive cells in the overlying epidermis. Zeng Z, Melamed J, Symmans PJ, Cangiarella JF, Shapiro RL, Peralta H, Symmans WF. Am J Surg Pathol. 1999 Nov;23(11):1349-55. PMID: 10555003
Mucinous cystadenocarcinoma of the breast. Koenig C, Tavassoli FA. Am J Surg Pathol. 1998 Jun;22(6):698-703. PMID: 9630176
Paget disease
Intraepidermal cytokeratin 7 expression is not restricted to Paget cells but is also seen in Toker cells and Merkel cells. Lundquist K, Kohler S, Rouse RV. Am J Surg Pathol. 1999 Feb;23(2):212-9. PMID: 9989849
Perianal Paget’s disease: a histologic and immunohistochemical study of 11 cases with and without associated rectal adenocarcinoma. Goldblum JR, Hart WR. Am J Surg Pathol. 1998 Feb;22(2):170-9. PMID: 9500217
Vulvar Paget’s disease: a clinicopathologic and immunohistochemical study of 19 cases. Goldblum JR, Hart WR. Am J Surg Pathol. 1997 Oct;21(10):1178-87. PMID: 9331290
Renal cell carcinomas
Renal cell carcinomas in children and young adults: increased incidence of papillary architecture and unique subtypes. Renshaw AA, Granter SR, Fletcher JA, Kozakewich HP, Corless CL, Perez-Atayde AR. Am J Surg Pathol. 1999 Jul;23(7):795-802. PMID: 10403302
