Cellular processes

Articles

• cellular necrosis
  4 February 2006

  Necrosis refers to a spectrum of morphologic changes that follow cell death in living tissue, largely resulting from the progressive degradative action of enzymes on the lethally injured cell (cells placed immediately in fixative are dead but not necrotic).
  As commonly used, necrosis is the gross and histologic correlate of cell death occurring in the setting of irreversible exogenous injury. Necrotic cells are unable to maintain membrane integrity and their contents often leak out. This (...)

• diapedesis
  30 April 2004

  leukocytic transmigration

• autophagy
  23 April 2004

  WKP
  Definition: Autophagy is the degradation of intracellular components in lysosomes.
  Autophagy is a cellular degradation pathway for the clearance of damaged or superfluous proteins and organelles. The recycling of these intracellular constituents also serves as an alternative energy source during periods of metabolic stress to maintain homeostasis and viability.
  To survive extreme environmental conditions, and in response to certain developmental and pathological situations, (...)

• antigen processing machinery
  22 April 2004

  antigen processing (APM)

• epithelial polarity
  26 January 2005

  See also:
  cell polarity
  References
  Suzuki A, Hirata M, Kamimura K, Maniwa R, Yamanaka T, Mizuno K, Kishikawa M, Hirose H, Amano Y, Izumi N, Miwa Y, Ohno S. aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity. Curr Biol. 2004 Aug 24;14(16):1425-35. PMID: #15324659#
  Zegers MM, O’Brien LE, Yu W, Datta A, Mostov KE. Epithelial polarity and tubulogenesis in vitro. Trends Cell Biol. 2003 Apr;13(4):169-76. PMID: #12667754#
  Stein M, (...)

• apoptosis
  25 June 2003

  GO:0006915 WKP
  Definition: Apoptosis is characterized by a series of dramatic perturbations to the cellular architecture that contribute not only to cell death, but also prepare cells for removal by phagocytes and prevent unwanted immune responses.
  See also : necroptosis
  Much of what happens during the demolition phase of apoptosis is orchestrated by members of the caspase family of cysteine proteases (CASPs).
  These proteases target several hundred proteins for restricted (...)

• cellular mechanics
  22 April 2004

  References
  Heidemann SR, Wirtz D. Towards a regional approach to cell mechanics. Trends Cell Biol. 2004 Apr;14(4):160-6. PMID: #15066633#

• chromosomal segregation
  2 July 2004

  Proper chromosome segregation is required to maintain the appropriate number of chromosomes from one cell generation to the next and to prevent aneuploidy, the condition in which a cell has gained or lost one or several chromosomes during cell division.
  Aneuploidy is a hallmark associated with birth defects and cancer, and is observed at relatively high frequencies in human somatic cells.
  Recent studies in mammalian tissue culture cells suggest that the persistence of (...)

• meiosis
  24 August 2004

  WP
  Definition: Meiosis is a specialized type of cell division leading to the production of gametes.
  During meiotic prophase I, homologous chromosomes interact with each other and form bivalents (pairs of homologous chromosomes).
  Three major meiotic processes — chromosome pairing, synapsis and recombination — are involved in the formation of bivalents.
  Chromosome pairing is largely dependent on the initiation and progression of recombination in fungi, mammals and plants, but not in (...)

• mitoses
  13 July 2003

  mitosis
  Images
  in a glandular epithelium
  https://twitter.com/BeynonMD/status/740787261046919169
  in epidermis
  https://twitter.com/doctormisti/status/
  numerous atypical mitoses
  https://twitter.com/smlungpathguy/status/743442537763971073
  Pathology
  abnormal mitosis / abnormal mitoses
  quantitative variations
  no mitosis
  anomalies of mitotic activity
  increased mitoses / increased mitotic activity
  low mitotic activity / inconspicuous mitoses
  moderate mitotic activity / (...)

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