Hyaluronan
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hyaluronic acid
5 February 2006 -
acetyl-CoA
2 June 2004Acetyl CoA
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02
4 February 2006ROS reactive oxygen species
O2 is converted to superoxide (O2-) by oxidative enzymes in the endoplasmic reticulum (ER), mitochondria, plasma membrane, peroxisomes, and cytosol.
O2- is converted to H2O2 by dismutation and thence to OH by the Cu2+/Fe2+-catalyzed Fenton reaction. H2O2 is also derived directly from oxidases in peroxisomes.
Resultant free radical damage to lipid (peroxidation), proteins, and DNA leads to various forms of cell injury.
02- superoxide catalyzes the reduction (...) -
H2O2
12 February 2006H(2)O(2)
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superoxide
4 February 200602-, superoxyde anion, superoxyde
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gene
16 September 2003WP
Definition: A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity.
The transmission of genes to an organism’s offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood (...) -
heme A
6 October 2003Pathology
anomalies of heme A synthesis COX15 deficiency -
methionine
15 October 2003Definition: Methionine (abbreviated as Met or M) is an essential α-amino acid with the chemical formula HO2CCH(NH2)CH2CH2SCH3. This essential amino acid is classified as nonpolar. Together with cysteine, methionine is one of two sulfur-containing proteinogenic amino acids.
Biosynthesis
As an essential amino acid, methionine is not synthesized in humans, hence we must ingest methionine or methionine-containing proteins.
In plants and microorganisms, methionine is synthesized via a pathway (...) -
nitric oxide
4 December 2003NO, nitric oxyde
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ABCA4
6 October 2003Pathology
autosomal recessive cone-rod dystrophy (#10958761#)
autosomal recessive Stargardt disease (STGD1)
fundus flavimaculatus (FFM)