miRNAs

• miR-130A
  2 May 2017

  Pathology
  miR-130A is a diagnostic marker to differentiate malignant mesothelioma from lung adenocarcinoma in pleural effusion cytology.
  References
  Diagnostic valu eof micoRNAs in asbestos exposure and malignant mesothelioma: systematic review and qualitative meta-analysis”, Minolucci, L, et al, June 1, 2016.
  MicroRNAs in mesothelioma: from tumour suppressors and biomarkers to therapeutic targets. 2016. doi:10.3978/j.issn.2072-1439.2015.04.56. (...)

• miR-143
  13 January 2017

  Mir143; miR143; MIR143
  Pathology
  MIR143-NOTCHs gene fusions in benign and malignant glomus tumors (#23999936#) MIR143-NOTCH1 gene fusions in benign and malignant glomus tumors (#23999936#) MIR143-NOTCH2 gene fusions in benign and malignant glomus tumors (#23999936#)
  See also
  miRNAs
  Open references
  Novel MIR143-NOTCH fusions in benign and malignant glomus tumors. Mosquera JM, Sboner A, Zhang L, Chen CL, Sung YS, Chen HW, Agaram NP, Briskin D, Basha BM, Singer S, Rubin MA, (...)

• miR-27a
  22 September 2015

  microRNA-27a
  Pathology
  osteosarcoma Down-regulation of microRNA-26a and up-regulation of microRNA-27a contributes to aggressive progression of human osteosarcoma. (#26377680#)
  Open references
  Down-regulation of microRNA-26a and up-regulation of microRNA-27a contributes to aggressive progression of human osteosarcoma. Taheriazam A, Bahador R, Karbasy SH, Jamshidi SM, Torkaman A, Yahaghi E, Shakeri M. Diagn Pathol. 2015 Sep 17;10(1):166. doi:10.1186/s13000-015-0400-3 . PMID: #26377680# (...)

• miR-26a
  22 September 2015

  microRNA-26a
  Pathology
  osteosarcoma Down-regulation of microRNA-26a and up-regulation of microRNA-27a contributes to aggressive progression of human osteosarcoma. (#26377680#)
  Open references
  Down-regulation of microRNA-26a and up-regulation of microRNA-27a contributes to aggressive progression of human osteosarcoma. Taheriazam A, Bahador R, Karbasy SH, Jamshidi SM, Torkaman A, Yahaghi E, Shakeri M. Diagn Pathol. 2015 Sep 17;10(1):166. doi:10.1186/s13000-015-0400-3 . PMID: #26377680# (...)

• miR-150
  14 September 2015

  miRNA-150
  Pathology
  Serum miR-150 can serve as a non-invasive biomarker for the diagnosis and prognosis of HCC patients. (#26215970#)
  Open references
  microRNA-150: a promising novel biomarker for hepatitis B virus-related hepatocellular carcinoma. Yu F, Lu Z, Chen B, Dong P, Zheng J. Diagn Pathol. 2015 Jul 28;10:129. doi:10.1186/s13000-015-0369-y . PMID: #26215970# (Free)

• miR-148
  14 September 2015

  miR-148a and miR-148b WKP
  miR-148 is a microRNA whose expression has been demonstrated in human (MI0000253), mouse (MI0000550), rat (MI0000616) and zebrafish (MI0002015). miR-148 has also been predicted in chicken (MI0001189).
  These predicted hairpin precursor sequence are related to those of miR-152, which has been expressed in mouse (MI0000174) and is predicted in human (MI0000462).[1]
  The hairpin precursors (represented here) are predicted based on base pairing and cross-species (...)

• miR-186
  6 September 2015

  Pathology
  MiR-186 suppresses the growth and metastasis of bladder cancer by targeting NSBP1. (#26290438#) miR-186 is the upstream regulator of NSBP1. miR-186-suppressed NSBP1 can be a novel therapeutic approach for bladder cancer.
  Open references
  MiR-186 suppresses the growth and metastasis of bladder cancer by targeting NSBP1. Yao K, He L, Gan Y, Zeng Q, Dai Y, Tan J. Diagn Pathol. 2015 Aug 20;10:146. doi:10.1186/s13000-015-0372- 3. PMID: #26290438# (...)

• Let-7g
  23 September 2014

  Pathology
  MicroRNAs MiR-218, MiR-125b, and Let-7g predict prognosis in patients with oral cavity squamous cell carcinoma. (#25050621#)
  Open References
  MicroRNAs MiR-218, MiR-125b, and Let-7g predict prognosis in patients with oral cavity squamous cell carcinoma. Peng SC, Liao CT, Peng CH, Cheng AJ, Chen SJ, Huang CG, Hsieh WP, Yen TC. PLoS One. 2014 Jul 22;9(7):e102403. doi:10.1371/journal.pone.0102403 . eCollection 2014. PMID: #25050621# (...)

• miR-218
  23 September 2014

  Pathology
  MicroRNAs MiR-218, MiR-125b, and Let-7g predict prognosis in patients with oral cavity squamous cell carcinoma. (#25050621#)
  Open References
  MicroRNAs MiR-218, MiR-125b, and Let-7g predict prognosis in patients with oral cavity squamous cell carcinoma. Peng SC, Liao CT, Peng CH, Cheng AJ, Chen SJ, Huang CG, Hsieh WP, Yen TC. PLoS One. 2014 Jul 22;9(7):e102403. doi:10.1371/journal.pone.0102403 . eCollection 2014. PMID: #25050621# (...)

• miRNAs
  10 September 2014

  MicroRNAs
  MicroRNAs (miRNAs) are small, approximately 20-nucleotide-long, non-coding single-stranded RNA molecules regulating the expression of target genes by imperfect (in animals) binding to the 3′-untranslated region (UTR) and possibly 5′-UTR of mRNA.
  To become the mature form, miRNAs are processed by enzymatic complexes Dorsha and Dicer, and they repress translation or lead to the degradation of the mRNA of their target genes.
  Currently approximately 2000 human miRNA sequences have (...)

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