Tumoral chromosomal anomalies

Articles

• t(13;19)(q14;p13)
  26 June 2007

  Pathology
  TCF3 rearrangements in B-cell precursor acute lymphoblastic leukemia (#17311319#)
  References
  Barber KE, Harrison CJ, Broadfield ZJ, Stewart AR, Wright SL, Martineau M, Strefford JC, Moorman AV. Molecular cytogenetic characterization of TCF3 (E2A)/19p13.3 rearrangements in B-cell precursor acute lymphoblastic leukemia. Genes Chromosomes Cancer. 2007 May;46(5):478-86. PMID: (...)

• t(6;11)(p21;q13)
  26 June 2007

  t(6;11)(p21;q12)

• homozygous deletions
  29 August 2007

  HDs

• t(11;14)(q13;q32)
  2 November 2005

  AGCOH
  Tumors
  B-cell lymphomas mantle cell lymphoma B-prolymphocytic leukaemia splenic lymphoma with villous lymphocytes chronic lymphocytic leukaemia multiple myeloma plasma cell leukaemia
  Genes involved
  CCND1 (BCL1) coding for cyclin-D1 at 11q13
  IGH at 14q32
  Links
  AGCOH
  References
  Combined molecular diagnosis of B-cell lymphomas with t(11;14)(q13;q32) or t(14;18)(q32;q21) using multiplex- and long distance inverse-polymerase chain reaction. Vieira L, Martinho A, Antunes O, (...)

• t(X;4)(q22;q31.3)
  2 December 2009

  Tumors
  giant cell reparative granuloma (#10565307#)
  References
  Novel karyotypes in giant cell-rich lesions of bone. Gleason BC, Kleinman PK, Debelenko LV, Rahbar R, Gebhardt MC, Perez-Atayde AR. Am J Surg Pathol. 2007 Jun;31(6):926-32. PMID: #17527082#

• 12p13 rearrangements
  19 March 2007

  Synopsis
  ETV6 rearrangements in Leukemias t(1;12)(q25;p13) t(1;12)(p36;p13) t(2;12)(q31;p13) t(3;12)(q26;p13) t(4;12)(q11-q21;p13) t(4;12)(p16;p13) t(5;12)(q33;p13) t(6;12)(p21;p13) in lymphoid malignancies t(7;12)(q36;p13) t(7;12)(p12;q13) t(7;12)(q34;p13) t(8;12)(q22;q13) t(9;12)(p24;p13) (SYK/ETV6) dic(9;12)(p13;p13) t(9;12)(q22;p12) t(9;12)(q34;p13) t(11;12)(p15;p13) t(11;12)(q23;q13) (/HMGA2) t(11;12)(q23;q13) (MLL/CIP29) t(12;12)(p13;q13) t(12;13)(p12;q12-14) t(12;14)(p13;q11) (...)

• del(9p)
  18 January 2006

  9p deletion
  Deletion of 9p21 is the most commonly reported chromosomal abnormality in pediatric acute lymphoblastic leukemia.
  Pathology
  del(9p) in precursor T lymphoblastic lymphoma (30%)
  Candidate genes
  CDKN2A

• del(5q)
  19 March 2007

  del(5)(q13q33)

• t(1;2)(p13;q37)
  5 October 2009

  1p13 and 2q37
  Tumors
  giant cell tumor of tendon sheath (#15768862#)
  References
  Giant cell tumor of tendon sheath arising in the toe. Occhipinti E, Heinrich SD, Craver R. Fetal Pediatr Pathol. 2004 Mar-Jun;23(2-3):171-9. PMID: #15768862#

• t(12;17)(q15;q23)
  2 December 2009

  Tumors
  extraorbital giant cell angiofibroma (#16527610#)
  References
  A t(12;17) in an extraorbital giant cell angiofibroma. Qian YW, Malliah R, Lee HJ, Das K, Mirani N, Hameed M. Cancer Genet Cytogenet. 2006 Mar;165(2):157-60. PMID: #16527610#

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