Molecular groups

Articles

• VEGFRs
  25 September 2003

  Vascular endothelial growth factor (VEGF) is a key regulator of physiological angiogenesis during embryogenesis, skeletal growth and reproductive functions.
  VEGF has also been implicated in pathological angiogenesis associated with tumors, intraocular neovascular disorders and other conditions.
  Non-signaling co-receptors also modulate VEGF RTK signaling. Currently, several VEGF inhibitors are undergoing clinical testing in several malignancies.
  The biological effects of VEGF are mediated (...)

• fatty acids
  25 October 2004

  Fatty acids provide highly efficient energy storage, storing much more energy for their weight than carbohydrates like glucose.
  Fatty acids are stored as triglycerides in adipose tissue, in which each triglyceride molecule contains three fatty acids and one glycerol. Triglycerides form fatty droplets that exclude water and take up minimal space.
  Fatty acids are also more highly reduced than carbohydrates, so they provide more energy during oxidation. The efficiency of energy storage in (...)

• myosins
  15 September 2003

  MYOs

• complex carbohydrates
  21 April 2004

  Complex carbohydrates are involved in recognition processes, including adhesion between cells, adhesion of cells to the extracellular matrix, and specific recognition of cells by one another.
  In addition, carbohydrates are recognized as differentiation markers and as antigenic determinants.
  Lectins are nonenzymatic proteins present in plants and animals, which preferentially bind to specific carbohydrate structures and play an important role in cell recognition.
  Modified carbohydrates (...)

• eicosanoids
  30 April 2004

  The eicosanoids are a family of lipophilic hormones derived from the twenty carbon fatty acid arachidonic acid.
  Most members of this family are rapidly metabolized near their site of synthesis, so they act locally on neighboring cells, not distant parts of the body. They are also not stored in cells, but synthesized rapidly in response to stimuli, making regulation of their synthesis a key to their activity.
  Many drugs act through modulating the production of eicosanoids or modulating (...)

• angiogenesis inhibitors
  20 April 2004

  angiogenesis inhibition, angiostatic treatment

• histones
  16 July 2003

  histone proteins

• cetone bodies
  2 June 2004

  The acetyl-CoA produced by mitochondrial beta-oxidation of fatty acids enters the Kreb’s cycle to produce energy, but that is not the only fate of acetyl-CoA.
  In liver mitochondria, some acetyl-CoA is converted to acetoacetate, beta-hydroxybutyrate, and acetone, collectively called ketone bodies.
  Ketone bodies are transported to other tissues such as brain, muscle or heart where they are converted back to acetyl-CoA to serve as an energy source.
  The brain normally uses only glucose for (...)

• homeobox proteins
  18 January 2006

  homeobox genes, HOXs

• pyrimidine
  25 August 2005

  pyrimidine nucleotide metabolism

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