AHR pathway at SABiosciences
AHR (Aryl Hydrocarbon Receptor) is a member of the bHLH (basic Helix–Loop–Helix)- PAS (Per-ARNT-Sim) family of transcriptional regulators that control a variety of developmental and physiological events, including Neurogenesis, Tracheal and Salivary duct formation, Toxin metabolism, Circadian rhythms, response to Hypoxia and Hormone Receptor function.
The unique feature of all bHLH-PAS proteins is the PAS domain, named after the first three proteins identified (...)
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Signaling pathways
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AHR pathway
23 November 2011 -
ATM/FANC/BRCA1/NBS1 signaling pathway
21 April 2004BRCAs signaling pathway, BRCAs-ATR-ARM signaling pathway; FANC/BRCA1/BRCA2/ATM/NBS1 signaling pathway
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Hippo signaling pathway
5 July 2007SWH pathway, Salvador-Warts-Hippo pathway WKP
Definition: The Salvador-Warts-Hippo (SWH) pathway, involved in tissue growth control in Drosophila melanogaster. At present, eleven proteins have been implicated as members of this pathway, and several downstream effector genes have been characterized.
The importance of this pathway is emphasized by its evolutionary conservation, and by increasing evidence that its deregulation occurs in human tumours.
Recent studies in Drosophila (...) -
PKA pathway
15 October 2003Activation of cAMP-dependent PKA pathway
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insulin signaling pathway
15 April 2005insulin signalling
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Ret pathway
6 October 2003Members: RET, GDNF, NRTN,
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molecular networks
17 October 2003References
Beyer A, Bandyopadhyay S, Ideker T. Integrating physical and genetic maps: from genomes to interaction networks. Nat Rev Genet. 2007 Sep;8(9):699-710. PMID: #17703239#
Lynch M. The evolution of genetic networks by non-adaptive processes. Nat Rev Genet. 2007 Oct;8(10):803-13. PMID: #17878896#
Basso K, Margolin AA, Stolovitzky G, Klein U, Dalla-Favera R, Califano A. Reverse engineering of regulatory networks in human B cells. Nat Genet. 2005 Apr;37(4):382-90. PMID: (...) -
BMPs signaling pathway
12 October 2007bone morphogenetic protein regulatory pathway, BMPs regulatory pathway, BMPs signaling pathway, BMPs signaling; bone morphogenetic protein (BMP) regulatory pathway
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Notch signaling pathway
11 June 2003Notch signalling pathway
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SFN signaling
10 November 201014-3-3Sigma Signaling
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