WKP
See also : ageing
Physiopathology
DNA somatic mutations, poor DNA repair and aging
As cells get older, the amount of DNA damage accumulates overtaking the rate of repair and resulting in a reduction of protein synthesis.
As proteins in the cell are used for numerous vital functions, the cell becomes slowly impaired and eventually dies. When enough cells in an organ reach such a state, the organ itself will become compromised and the symptoms of disease begin to manifest. (...)
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