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Cellular systems
Articles
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mononuclear phagocyte and dendritic cell system
24 October 2003 -
ERGIC
3 June 2006endoplasmic reticulum-Golgi intermediate compartment
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protein-sorting apparatus
3 June 2006Pathology
genetic diseases of intracellular-membrane transport diseases affecting the protein-sorting apparatus germline mutations of LMAN1 in combined deficiency of coagulation factors V and VIII
References
Olkkonen VM, Ikonen E. Genetic defects of intracellular-membrane transport. N Engl J Med. 2000 Oct 12;343(15):1095-104. PMID: #11027745# -
trans-Golgi network
3 June 2006The trans-Golgi network (TGN) is a major sorting centre for cell lipids and proteins at the crossroads of the endocytic and exocytic pathways; it has a complex dynamic structure composed of a network of tubular membranes that generate pleiomorphic carriers targeted to different destinations.
The composition and identity of cell organelles are dictated by the flux of lipids and proteins that they receive and lose through cytosolic exchange and membrane trafficking.
See also
Golgi (...)
