Definition: Hypertrophy refers to an increase in the size of cells, resulting in an increase in the size of the organ.
Pathogenesis
The hypertrophied organ has no new cells, just larger cells. The increased size of the cells is due not to cellular swelling but to the synthesis of more structural components.
Cells capable of division may respond to stress by undergoing both hyperplasia and hypertrophy, whereas in nondividing cells (e.g., myocardial fibers), hypertrophy occurs.
Nuclei (...)
Home > Keywords > Morphological anomalies > Microscopical anomalies
Microscopical anomalies
Elementary lesions; microscopical lesions
Articles
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hypertrophy
3 June 2003 -
metaplasia
11 July 2003Definition: Metaplasia is the reversible replacement of one differentiated cell type with another differentiated cell type.
Metaplasia causes precursor cells to change their cell fate, and do not change existing differentiated cells.
Metaplasia is reversible and usually occurs in response to chronic irritation and inflammation and allows for substitution of cells that are better able to survive under circumstances in which a more fragile cell type might succumb.
Metaplasia is a (...) -
colonic cryptitis
29 May 2004colonic glandulitis
Etiology (Examples)
IBDs Crohn colitis ulcerative colitis
acute colitis infectious colitis
See also
colonic mucosal anomalies colonic cryptic anomalies -
bridging necrosis
27 January 2004Definition: Bridging necrosis is the term given to confluent necrosis linking terminal venules to portal tracts. The term "Bridging necrosis" has been used for necrosis linking any of the vascular structures, but it is now more often restricted to the linking of terminal hepatic venules (centrilobular veins) to portal tracts (central-portal bridging necrosis).
Bridging necrosis describes the location rather than the type of necrosis. It usually results from extensive necrosis of confluent (...) -
abscess
9 June 2004abcesses
Definition: Abscesses are localized collections of purulent inflammatory tissue caused by suppuration buried in a tissue, an organ, or a confined space. They are produced by deep seeding of pyogenic bacteria into a tissue.
Abscesses have a central region that appears as a mass of necrotic leukocytes and tissue cells. There is usually a zone of preserved neutrophils around this necrotic focus, and outside this region vascular dilation and parenchymal and fibroblastic proliferation (...) -
intimal fibrosis
12 March 2004fibrous intimal thickening, concentric intimal thickening, fibrous intimal thickening
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streak gonad
17 January 2007Digital cases
Case 271 : 46,XY Pure gonadal dysgenesis. Streak gonad.
Synopsis
streak gonad with fibrous tissue resembling ovarian stroma
Etiology
constitutional monosomy X (Turner syndrome)
SOX9 mutations (campomelic dysplasia) [Rodriguez 1993; Meyer et al. 1997; Velagaleti et al. 2005]
See also
gonadal agenesis
gonadal lesions
gonadal lesional syndromes
gonadal (...) -
adrenal cytomegaly
18 January 2006PO
Definition: Adrenal cytomegaly is characterized by the presence of large polyhedral cells with eosinophilic granular cytoplasm and enlarged nuclei in the adrenal cortex. Adrenal cytomegaly is found in 0.8% pediatric autopsies.
Adrenal cytomegaly is relatively common finding within fetal cortex in newborns, particularly premature infants (3-7%) or infants with Rh incompatibility.
Adrenal cytomegaly may be associated with Beckwith-Wiedemann syndrome
Focal adrenal cytomegaly can be (...) -
alveolar hyaline membranes
12 February 2004Etiology
diffuse alveolar damage (acute respiratory distress syndrom)e)
neonatal hyalin membranes disease
See also
Lungs pulmonary lesions alveolar content -
hyaline globules
14 October 2003Eosinophilic hyaline globules
See also : cytoplasmic inclusions
Images
Eosinophilic hyaline globules in yolk sac tumors https://twitter.com/HenryTranMD/status/715457178912428032 https://twitter.com/DrAldehyde/status/893837144397053955
intracytoplasmic hyaline globules in clear cell RCC https://twitter.com/MoravekMD/status/1093981605738225664 https://twitter.com/slusagar/status/1169309473648734213
Etiology
hyaline globules in diseases alpha-1-antitrypsine deficiency rete testis (...)