Humpath.com - Human pathology

Most recent articles

• nail

  25 March

  Adj. ungueal WKP
  Definition : A nail is a horn-like envelope covering the tips of the fingers and toes in most primates and a few other mammals. Nails are similar to claws in other animals. Fingernails and toenails are made of a tough protective protein called alpha-keratin. This protein is also found in the hooves and horns of different animals.

• odontogenic cysts

  25 March

  WKP
  Definition : Odontogenic cyst are a group of jaw cysts that are formed from tissues involved in odontogenesis (tooth development).
  Odontogenic cysts are closed sacs, and have a distinct membrane derived from rests of odontogenic epithelium. It may contain air, fluids, or semi-solid material.
  Intra-bony cysts are most common in the jaws, because the mandible and maxilla are the only bones with epithelial components.
  That odontogenic epithelium is critical in normal tooth (...)

• salivary gland tumors with cribriform/canalicular growth pattern

  18 March, by admin

  Examples
  adenoid cystic carcinoma
  cribriform adenocarcinoma of minor salivary glands
  polymorphous adenocarcinoma
  pleomorphic adenoma
  canalicular adenoma
  See also
  salivary gland tumors
  cribriform/canalicular growth pattern / cribriform-canalicular pattern

• PIK3CA-related overgrowth spectrum disorder

  16 March

  Cancer-Associated PIK3CA Mutations in Overgrowth Disorders
  See also : PIK3CA
  Definition : PIK3CA is one of the most commonly mutated genes in solid cancers. PIK3CA mutations are also found in benign overgrowth syndromes, collectively known as PIK3CA-related overgrowth spectrum (PROS).
  As in cancer, PIK3CA mutations in PROS arise postzygotically, but unlike in cancer, these mutations arise during embryonic development, with their timing and location critically influencing the resulting (...)

• RET-rearranged tumors

  16 March

  RET-driven cancers
  Types (Examples)
  RET-rearranged carcinomas RET-rearranged thyroid carcinomas RET-rearranged pulmonary adenocarcinoma RET-rearranged colorectal adenocarcinoma
  RET-rearranged fusiform cell tumors

• fusiform cells in nodal FNA

  14 March

  Examples
  history of medullary thyroid CA (MTC) "spindle cell variant" - metastasis from the known thyroid primary https://twitter.com/sza_jhcyto/status/1105893402573504513
  See also
  nodal FNA

• smallpox

  13 March

  Examples
  A patient with smallpox in 1912. https://twitter.com/PastMedHistory/status/1097410965488967680

• giant cell variant of medullary thyroid carcinoma

  13 March

  Examples
  giant cell variant of Medullary thyroid carcinoma (MTC) MTC variants typically carry the same prognosis as the conventional type. DD : ATC and Mets to the thyroid. https://twitter.com/sza_jhcyto/status/1105511218536738818
  Paywall references
  Fine needle aspiration cytology of medullary carcinoma of the thyroid with a focus on rare variants: a review of 78 cases. Kaushal S, Iyer VK, Mathur SR, Ray R. Cytopathology. 2011 Apr;22(2):95-105. doi:10.1111/j.1365-2303.2010.00747.x. (...)

• giant cell on thyroid FNA

  13 March

  Examples
  giant cell variant of Medullary thyroid carcinoma (MTC) MTC variants typically carry the same prognosis as the conventional type. DD : ATC and Mets to the thyroid. https://twitter.com/sza_jhcyto/status/1105511218536738818

• plasmacytoid tumors

  13 March

  Examples
  plasmacytic tumors
  plasmacytoid melanoma
  plasmacytoid urothelial carcinoma https://twitter.com/Rus13Co/status/1105737198928826368
  See also
  plasmacytoid appearance

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