Humpath.com - Human pathology

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• cobble stone appearance

  12 January

  Examples
  macroscopical appearance of ileal mucosa in ileal Crohn disease
  See also
  cobble stone arrangement

• HPV E6/E7 mRNA in situ hybridization

  12 January

  HPV E6/E7 mRNA In Situ Hybridization
  Paywall references
  HPV E6/E7 mRNA In Situ Hybridization in the Diagnosis of Cervical Low-grade Squamous Intraepithelial Lesions (LSIL). Mills et al. The American Journal of Surgical Pathology: February 2018 - Volume 42 - Issue 2 - p 192–200
  doi:10.1097/PAS.0000000000000974.
  https://journals.lww.com/ajsp/Citation/2018/02000/HPV_E6_E7_mRNA_In_Situ_Hybridization_in_the.7.aspx

• HSIL

  12 January

  The cells of HSIL have a high N/C ratio with smaller cell size than found in LSIL. They are hyperchromatic and have irregular nuclear contours. HSIL does not typically show koilocytic change on cytology.
  Images
  HSIL https://twitter.com/BellaMicheleang/status/784279128472117250 https://twitter.com/JMGardnerMD/status/841650655202803715
  H-SIL cells with "line of ants" appearance (...)

• Infections in PAP smear

  12 January

  See also
  cervical cytology

• HPV-associated lower anogenital squamous lesions

  12 January

  See also : HPV-associated lesions
  Open references
  The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: Background and Consensus Recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology. https://doi.org/10.5858/arpa.LGT200570.
  http://www.archivesofpathology.org/doi/10.5858/arpa.LGT200570?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

• HPV-associated lesions

  12 January

  Types
  HPV-associated squamous cell carcinoma HPV-associated oropharyngeal squamous cell carcinoma HPV-associated head and neck squamous cell carcinoma HPV-associated tumors HPV-associated oral intraepithelial neoplasia lingual HPV-associated adenocarcinoma HPV-associated cervical squamous cell carcinoma HPV-associated oropharyngeal carcinomas HPV-associated adenocarcinoma pulmonary metastasis of HPV-associated SCCOP HPV-associated Bowen disease HPV-associated (...)

• SOX10+

  12 January

  Definition : SOX10 is a newer Schwannian and melanocytic marker that has generated great interest for its relative sensitivity and specificity in the diagnosis of neural crest-derived tumors.
  SOX10 in melanocytic tumors
  SOX10 is a melanoma marker (100%, Appl Immunohistochem Mol Morphol 2014;22:142)
  melanocytic nevi are positive (Nat Cell Biol 2012;14:882),
  desmoplastic melanoma may be only focally positive (Appl Immunohistochem Mol Morphol 2013;21:506)
  MITF1 and SOX10 can be (...)

• central small nucleus

  12 January

  Central small nuclei
  Examples
  granular cell tumor https://twitter.com/NMacagnoMD/status/1068226203268583424
  See also
  nuclear appearance
  nuclear anomalies
  nucleus / nuclei

• cellular shape

  12 January

  cell shape
  Pathology
  anomalies of cellular shape tumoral cell shape fusiform tumoral cells round tumoral cells
  See also
  cellualr appearance
  cellular size tumoral cell size small tumoral cells middle-size tumoral cells large tumoral cells

• cellular size

  12 January

  cell size
  Pathology
  anomalies of cellular size
  See also
  cellular appearance cellular shape

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