Humpath.com - Human pathology

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• atypical oxyphilic metaplasia

  7 December

  Definition : incidental finding of endocervical glands lined by large cuboidal or polygonal epithelial cells with dense, eosinophilic, focally vacuolated cytoplasm and variable nuclear enlargement, hyperchromatism, multiple lobes or multinucleation; no mitotic activity or stratification; benign behavior (Int J Gynecol Pathol 1997;16:99)

• endocervical glandular atypia

  7 December

  endocervical glandular dysplasia ; endocervical glandular dysplasia (atypical hyperplasia) ; United Kingdom CGIN : cervical glandular intraepithelial neoplasia ; Glandular dysplasia PO
  Synopsis
  Glandular atypia Glandular cells with hyperchromatic nuclei with only occasional mitotic figures and minimal pseudostratification No cribriform areas, no papillary projections, no crowding, no mitotic figures Alternatively there is marked atypia involving only a single gland Normal N/C ratio (...)

• cervical glandular anomalies

  7 December

  Types
  cervical adenocarcinoma endocervical glandular atypia / endocervical glandular dysplasia (PO) adenocarcinoma in situ (PO)

• cervical anomalies

  7 December

  Types
  cervical squamous anomalies
  cervical glandular anomalies

• aponeurosis

  6 December, by admin

  Definition : An aponeurosis is a type or a variant of the deep fascia, in the form of a sheet of pearly-white fibrous tissue that attaches sheet-like muscles needing a wide area of attachment.
  Their primary function is to join muscles and the body parts they act upon, whether bone or other muscles.

• fascia

  6 December

  WKP
  A fascia is a band or sheet of connective tissue, primarily collagen, beneath the skin that attaches to, stabilizes, encloses, and separates muscles and other internal organs.
  Fascia is classified by layer, as superficial fascia, deep fascia, and visceral or parietal fascia, or by its function and anatomical location.
  Like ligaments, aponeuroses, and tendons, fascia is made up of fibrous connective tissue containing closely packed bundles of collagen fibers oriented in a wavy (...)

• PI3K

  27 November

  Phosphoinositide 3-kinase
  See also : PI3Ks

• PI3K-mutated colorectal adenocarcinoma

  27 November

  See also
  PI3K

• colorectal adenocarcinoma biomarkers

  27 November

  Types
  KRAS mutations
  NRAS mutations
  RAF mutations
  PI3K mutations
  Tumorigenesis pathways
  tubular adenoma pathway
  serrated pathway
  See also
  colorectal adenocarcinoma

• KRAS-mutated cancers

  27 November

  Examples
  KRAS-mutated colorectal adenocarcinoma
  KRAS-mutated pulmonary adenocarcinoma
  KRAS-mutated medullary thyroid carcinoma
  See also
  KRAS
  KRAS mutations

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