Humpath.com - Human pathology

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• placental calcifications

  17 May

  placental calcification
  See also
  placental anomalies
  calcifications

• mammary carcinoma with medullary features

  14 May

  Carcinoma with medullary features (CMF) of the breast
  |PO|
  Definition: Carcinoma with medullary features (CMF) includes :
  mammary medullary carcinoma
  atypical medullary carcinoma
  invasive carcinoma, no special type (NST) with features of pushing borders, syncytial growth, high grade nuclei and prominent lymphoid infiltrate.
  WHO Classification of Tumors of the Breast (2013) recommends using the term Carcinoma with medullary features (CMF) rather than medullary carcinoma or (...)

• KL

  14 May

  Klotho WKP
  Definition: Klotho is an enzyme that in humans is encoded by the KL gene.
  The KL gene encodes a type-I membrane protein that is related to β-glucuronidases.
  Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF.
  Also, mutations within the KL protein have been associated with ageing, bone (...)

• anal pathology

  8 May

  Pathology : anal pathology
  anal malformations
  anal anomalies
  anal lesional syndromes
  anal diseases
  anal tumors
  congenital defects
  Infectious diseases
  Inflammatory diseases Crohn disease fissure fistula granuloma inguinale HIV lymphogranuloma venereum lymphoid polyp syphilis ulcer ulcerative colitis
  Benign anomalies / non-neoplastic lesions granular cell tumor hemorrhoids hypertrophic HSV hypertrophied papillae Hirschsprung inflammatory cloacogenic polyp internal anal (...)

• broad ligament tumors

  8 May

  Pathology
  broad ligament tumors ependymoma leiomyoma leiomyosarcoma remnants serous tumors
  See also
  broad ligament
  tumors
  tubal pathology
  uterine pathology

• broad ligament

  8 May

  Pathology
  broad ligament tumors ependymoma leiomyoma leiomyosarcoma remnants serous tumors
  See also
  tubal pathology
  uterine pathology

• tubal pathology

  8 May

  Fallopian tube pathology
  Pathology : tubal pathology
  fallopian tube malformations
  fallopian tube anomalies
  tubal epithelial anomalies
  fallopian tube diseases
  fallopian tube tumors
  tubal inflammation : salpingitis
  acute inflammation salpingitis
  chronic inflammation salpingitis
  foreign body salpingitis
  granulomatous salpingitis
  ligneous salpingitis
  pseudoxanthomatous salpingitis
  xanthogranulomatous salpingitis
  benign diseases /non-neoplastic diseases
  amyloidosis (...)

• MME

  8 May

  CD10 WKP
  See also : CD10

• oncohistones

  8 May

  Definition: Recurrent mutations in histone genes can cause pediatric cancers. These mutations occur at high frequency and lead to the expression of mutant histones that exhibit oncogenic features. Thus, they are termed oncohistones.
  Mutations have been found in the genes encoding histone H3 and its variants.
  The expression of the oncohistones affects the global chromatin landscape.
  Paywall references
  Oncohistones: drivers of pediatric cancers. Mohammad F, Helin K. Genes Dev. 2017 Dec (...)

• advanced glycation end-products

  7 May

  AGEs; advanced glycation end-product
  Definition: Advanced glycation end products (AGEs) are proteins or lipids that become glycated as a result of exposure to sugars, or glycation.
  Pathology
  Advanced glycation end products (AGEs) can be a factor in aging and in the development or worsening of many degenerative diseases, such as diabetes, atherosclerosis, chronic kidney disease, and Alzheimer’s disease.
  See also (...)

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