Etiology
In a case of granulomatous mastitis due to Corynebacterium kroppenstedtii, a strongly impaired neutrophil responses to Nod2 agonist and a single nucleotide polymorphism within the NOD2 gene (SNP13 [Leu1007fsinsC]) in a heterozygous state have been found. These findings provided a demonstration of impaired Nod2 function associated with corynebacterial infection. (#19641059#)
References
First description of NOD2 variant associated with defective neutrophil responses in a woman (...)
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