Functional proteic groups

Articles

• growth factors
  21 November 2003

  GFs

• NLRs
  11 January 2008

  NOD-like receptors (NLRs)

• TOPs
  26 March 2006

  topoisomerases

• chemokine receptors
  8 March 2004

  Members CCRs CXCRs
  Features
  chemokine receptor-positive cells
  References
  Tran PB, Miller RJ. Chemokine receptors: signposts to brain development and disease. Nat Rev Neurosci. 2003 Jun;4(6):444-55. PMID: #12778117#

• Na+ channels
  22 March 2005

  References
  Herfst LJ, Rook MB, Jongsma HJ. Trafficking and functional expression of cardiac Na+ channels. J Mol Cell Cardiol. 2004 Feb;36(2):185-93. PMID: #14871545#

• chemokines
  18 November 2003

  Chemotactic cytokines

• protein phosphatases
  1 December 2003

  Mitosis exit
  The mitosis-to-interphase transition involves dramatic cellular reorganization from a state that supports chromosome segregation to a state that complies with all functions of an interphase cell.
  This process, termed mitotic exit, depends on the removal of mitotic phosphorylations from a broad range of substrates.
  Mitotic exit regulation involves inactivation of mitotic kinases and activation of counteracting protein phosphatases.
  The key mitotic exit phosphatase in budding (...)

• vesicular coat proteins
  29 October 2003

  Proteins and lipids to be transported are sorted to specific sites on the donor membrane, or compartment, and transport vesicles bud with the aid of cytosolic complexes of coat proteins.
  Vesicles move along cytoskeletal tracks, either microtubules or actin filaments, with the help of motor proteins.
  The vesicle is tethered and docked near the target membrane and subsequently fuses with the acceptor bilayer, releasing its contents into the target, or acceptor, compartment.
  Vesicular coat (...)

• intramembrane-cleaving proteases
  29 November 2003

  References
  Martoglio B, Golde TE. Intramembrane-cleaving aspartic proteases and disease: presenilins, signal peptide peptidase and their homologs. Hum Mol Genet. 2003 Oct 15;12 Spec No 2:R201-6. PMID: #12966028#
  Weihofen A, Martoglio B. Intramembrane-cleaving proteases: controlled liberation of proteins and bioactive peptides. Trends Cell Biol. 2003 Feb;13(2):71-8. PMID: (...)

• cytosolic signaling proteins
  4 December 2003

  cytoplasmic signalling proteins, cytoplasmic signaling proteins

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