Functional proteic groups

Articles

• calcium regulating proteins
  6 September 2005

  Ca++ regulating proteins

• bacterial toxins
  12 November 2003

  References
  Lax AJ. New genotoxin shows diversity of bacterial attack mechanisms. Trends Mol Med. 2007 Jan 16; PMID: #17234453#
  Fasano A. Toxins and the gut: role in human disease. Gut. 2002 May;50 Suppl 3:III9-14. PMID: #11953326#

• chemokines
  18 November 2003

  Chemotactic cytokines

• MMPs
  29 October 2003

  matrix metalloproteases, matrix metalloproteinases
  Definition: Increased expression of matrix metalloproteinases (MMPs) is associated with nearly every tumor type. Although many studies have shown that MMPs can promote malignancy, recent evidence has revealed that MMPs can play a causative role also in the earliest stages of cancer development.
  MMPs not only compromise cell-cell and cell-substratum adhesion processes that impact genomic surveillance mechanisms but also act directly on (...)

• TOPs
  26 March 2006

  topoisomerases

• voltage-gated ion channel
  26 January 2005

  voltage-gated ion channels

• growth factor receptors
  21 November 2003

  References
  Leof EB. Growth factor receptor signalling: location, location, location. Trends Cell Biol. 2000 Aug;10(8):343-8. PMID: #10884687#

• nuclear hormone receptors
  23 November 2003

  NHRs

• adaptator proteins
  16 July 2004

  adaptators

• DNA methyltransferases
  21 November 2003

  Patterns of DNA methylation are laid out during early embryogenesis via the interplay of at least three active DNA methyltransferases, DNMT1, DNMT3A, and DNMT3B, and targeted deletions of these genes in the mouse have demonstrated that the enzymes are essential for normal development.
  DNMT1 associates with the DNA replication fork and functions as a hemi-methylase responsible for maintaining correct methylation patterns on DNA replication. DNMT3s (DNMT3A and DNMT3B) are instead de novo (...)

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