Chromosomal regions

Articles

• 3q29 region
  6 June 2005

  Pathology
  3q29 microdeletion syndrome
  3q29 amplification

• 12q14 region
  13 June 2005

  Cytogentics
  translocations in tumors 12q14 and 7p12 12q14 and 8q22 12q14 and 11q23 12q14 and 12p11 12q14 and 14q31 12q14 and 20q11
  amplification in tumors with genic overexpression targer genes: CDK4
  Molecular biology HMGA2 fusion genes truncated HMGA2 isoforms
  Tumors
  lipomas

• a12p
  15 June 2005

  12p arm

• Xq22 region
  31 May 2005
• 15q26 region
  8 June 2005

  Pathology
  partial monosomy 15q26 facial dysmorphism absent nasal bone clinodactyly rocker-bottom feet diaphragmatic hernia severe growth restriction two-vessel cord
  15q26 amplification

• 2q arm
  28 September 2004

  2q

• 7q22 region
  13 June 2005

  7q22 LOH in tumors
  uterine leiomyoma (13%) (#15676150#)
  References
  Sell SM, Tullis C, Stracner D, Song CY, Gewin J. Minimal interval defined on 7q in uterine leiomyoma. Cancer Genet Cytogenet. 2005 Feb;157(1):67-9. PMID: #15676150#

• 20q13 region
  24 August 2004

  Pathology
  20q13 amplification in tumors
  Amplification at 20q13 occurs in a variety of tumor types and is associated with aggressive tumor behavior. Kallioniemi et al. (1994) found increased copy number involving 20q13 in 40% of breast cancer cell lines and 18% of primary breast tumors.
  Other comparative genomic hybridization studies revealed copy number gains at 20q13 in greater than 25% of cancers of the ovary (ovarian carcinomas), colon (colonic adenocarcinomas), head and neck (head (...)

• 6q LOH
  15 September 2004

  Tumors or lesions
  liver-cirrhosis nodules (33%) (#15362568#)
  Regions
  6q25 LOH pulmonary carcinomas