The novel aphidicolin-inducible common fragile site FRA9G maps to chromosomal band 9p22.2.
The fragile DNA sequence extends over a genomic region of approximately 300 kb within the C9orf39 (chromosome 9 open reading frame 39) gene.
Analysis of incidence in healthy individuals showed that FRA9G is commonly expressed in the population.
Heterozygous BRCA2 mutation carriers exhibit an almost sevenfold increase of FRA9G expression compared to an unrelated control population group.
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Home > Keywords > Cytogenetics > Fragile sites
Fragile sites
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FRA9G
29 August 2007 -
common fragile sites
26 June 2007CFS