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Home > G. Tumoral pathology > translocation-associated sarcomas

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translocation-associated sarcomas

Exemples

- alveolar rhabdomyosarcoma

- myxoid liposarcoma

- congenital fibrosarcoma and cellualr mesoblastic nephroma

- dermatofibrosarcoma protuberans/giant cell fibroblastoma:

- alveolar soft part sarcoma

- synovial sarcoma

- Ewing sarcoma/Primitive neuroectodermal tumor

  • t(11;22)(q24;q12) (EWS-FLI1)
  • t(21;22)(q22;q12) (EWS-ERG) (ERG at 21q22)
  • t(7;22)(p22;q12) (EWS-ETV1) (ETV1 at 7p22)
  • t(17;22)(q12;q12) (EWS-E1AF) (E1AF at 17q12)
  • t(2;22)((q33;q12) (EWS-FEV) (FEV at 2q23)
  • t(22;22)(q1;q12) (EWS-ZSG)

- epithelioid sarcoma

- desmoplastic small round cell tumor

  • t(11;22)(p13;q12) (EWS-WT1)

- extraskeletal myxoid chrondrosarcoma

- clear cell sarcoma of the soft tissue (soft part melanoma)

- angiomatoid fibrous histiocytoma

- endometrial stromal sarcoma

- low-grade fibromyxoid sarcoma

  • t(7;16)(q33;p11) (FUS-CREB3L2)
  • t(11;16)(p11;p11) (FUS-CREB3L1)

- inflammatory myofibroblastic tumor

  • t(1;2)(q22;q23) (TPM3-ALK)
  • t(2;19)(p23;p13) (TPM4-ALK)
  • t(2;17)(p23;p13) (CLTC-ALK)
  • t(2;2)(p23;q13) (RANBP2-ALK)

See also

- Sarcomas

References

- Montgomery E, Argani P, Hicks JL, DeMarzo AM, Meeker AK. Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically. Am J Pathol. 2004 May;164(5):1523-9. PMID: 15111298

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