Immunophenotype
+ | TdT | CD19 | CD79a | ||||
- | CD3 | ||||||
+/- | CD10 | CD24 | CD20 | CD22 | CD45 | CD13 | CD33 |
Cytogenetics
t(9;22)(q34;q11) (BCR/ABL) (BCR at 9q34 and ABL at 22q11)
t(v;11))v;q23) (v/MLL) (MLL rearrangement at 11q23) (CD10-, CD24-, CD15+)
t(12;21)(p13;q22) (ETV6/RUNX1 or TEL/AML1) (ETV6 at 12p13 and RUNX1 at 21q22) (cd10+, CD34-, CD20-)
t(1;19)(q23;p13) (PBX1/TCF3 or PBX/E2A) (PBX1 at 1q23 and TCF3 at 19p13) (CD10+, CD34-, CD20-, mu +)
hypodiploid
hyperdiploid >50
deletions
- del(6q)
- del(9p)
- del(12p)
hyperdiploid <51
near tumoral triploidy
near tumoral tetraploidy
See also