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19p13

Thursday 20 October 2005

Target genes

TCF3 (E2A)
LYL1

Pathology

19p13 rearrangements in leukemias

t(1;19)(q23 ;p13) in acute pre-B lymphoblastic leukemia leukemia (B-ALL) (TCF3/PBX1 fusion gene)
t(7;19)(q34 ;p13) in T-cell acute lymphoblastic leukemia (T-ALL) (LYL1/TCRB fusion gene)

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