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CASP9

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CASP9 and the PI3K/PTEN/AKT signaling pathway (From Biocarta)

The genes encoding Caspase-9 has been mapped to chromosome region 1p36.2, a region alleged to involve one or several tumour suppressor genes in neuroblastoma tumours.

See also

- CASPs

References

- Abel, F.; Sjoberg, R.-M.; Ejeskar, K.; Krona, C.; Martinsson, T. : Analyses of apoptotic regulators CASP9 and DFFA at 1p36.2, reveal rare allele variants in human neuroblastoma tumours. Brit. J. Cancer 86: 596-604, 2002. PubMed ID : 11870543