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Home > A. Molecular pathology > transcription factors

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transcription factors

Classification

CHXs ETSs EYAs HOXs FOXs LIMs LMXs MSXs OTXs
PAXs PHOXs PITXs POUs PPARs SOXs TBXs VSXs ZNFs

Pathology (Exemples)

- transcription factors in cancer
- transcription factors in developmental anomalies (developmental disorders)

Transcription factors and developmental disorders (Exemples)

- TBX5 mutations in Holt-Oram syndrome (TBXs)
- LMX1B mutations in nail-patella syndrome (LIMs)

Transcription factors in cancer (Exemples)

- transcription factor fusion gene formation by translocation
- transcription factor gene mutations

Pathology by molecular groups

CHXs
ETSs
FOXs
HOXs
LIMs
MSXs
OTXs
PAXs
PHOXs
PITXs
POUs
PPARs
SOXs
TCFs
TCF2 type diabetes renal cysts and diabetes renal dysplasia
VSXs
TBXs
ZNFs

See also

- lineage-specific transcription factors

References

- Darnell JE Jr. Transcription factors as targets for cancer therapy. Nat Rev Cancer. 2002 Oct;2(10):740-9. PMID: 12360277

- Hart SM. Modulation of nuclear receptor dependent transcription. Biol Res. 2002;35(2):295-303. PMID: 12415747

Keywords