Human pathology

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stroke

Definition: An ischemic stroke is a cerebrovascular accident that results from occlusion of cerebral arteries owing to atherosclerosis and leading to a neurological deficit or death.

References

- Gulcher JR, Gretarsdottir S, Helgadottir A, Stefansson K. Genes contributing to risk for common forms of stroke. Trends Mol Med. 2005 May;11(5):217-24. PMID: 15882609

- Zheng Z, Lee JE, Yenari MA. Stroke: molecular mechanisms and potential targets for treatment. Curr Mol Med. 2003 Jun;3(4):361-72. PMID: 12776991

- Lo EH, Dalkara T, Moskowitz MA. Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci. 2003 May;4(5):399-415. PMID: 12728267

- Tournier-Lasserve E. New players in the genetics of stroke. N Engl J Med. 2002 Nov 21;347(21):1711-2. PMID: 12444190