Human pathology

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pulmonary fibroleiomyomatous hamartoma

solitary fibroleiomyomatous hamartoma of the lung

Synopsis

- solitary well-demarcated tumor
- solid nodule without hemorrhage or necrosis
- 1.5 cm in diameter
- proliferation of fibromuscular tissue in interlacing fascicles
- many tubular or cleft-like epithelial inclusions
- epithelial inclusions with cystic changes and goblet cell metaplasia
- no atypical changes
- Other mesenchymal components such as cartilaginous, myxomatous or adipose tissues not seen.

Differential diagnosis

- so-called fibroleiomyomatous hamartoma or benign metastasizing leiomyoma, usually found in the lungs of women who have had hysterectomies, as multiple fibromuscular nodules

See also

- fibromuscular tumors of the lung.

References

- Itoh H, Yanagi M, Setoyama T, Shirao K, Yanagi S, Kataoka H, Shimotakahara T, Koono M. Solitary fibroleiomyomatous hamartoma of the lung in a patient without a pre-existing smooth-muscle tumor. Pathol Int. 2001 Aug;51(8):661-5. PMID: 11564224