mesoblastic nephroma
Variants
cellular mesoblastic nephroma
cystic mesoblastic nephroma (1332189)
myoid differentiation (12149722)
Cytogneetics
trisomy 11 (17639583)
translocation t(12-15)(p13;q25) creating ETV6/NTRK3 gene fusion in cellular mesoblastic nephroma
Molecular biology
elevated expression levels of IGF2 mRNA in congenital mesoblastic nephroma of the cellular or mixed type with trisomy 11 (17639583)
ETV6/NTRK3 gene fusion by t(12-15)(p13;q25) in cellular mesoblastic nephroma
Evolution
rare metatstasis (8385324)
See also
-
renal tumors
- pediatric renal tumors
References
Watanabe N, Haruta M, Soejima H, Fukushi D, Yokomori K, Nakadate H, Okita H, Hata JI, Fukuzawa M, Kaneko Y. Duplication of the paternal IGF2 allele in trisomy 11 and elevated expression levels of IGF2 mRNA in congenital mesoblastic nephroma of the cellular or mixed type. Genes Chromosomes Cancer. 2007 Oct;46(10):929-35. PMID: 17639583
Vujanic GM, Delemarre JF, Moeslichan S, Lam J, Harms D, Sandstedt B, Voute PA. Mesoblastic nephroma metastatic to the lungs and heart?another face of this peculiar lesion: case report and review of the literature. Pediatr Pathol. 1993 Mar-Apr;13(2):143-53. PMID: 8385324
Vujanic GM. Congenital cystic mesoblastic nephroma: a rare cystic renal tumour of childhood. Case report. Scand J Urol Nephrol. 1992;26(3):315-7. PMID: 1332189