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Home > E. Pathology by systems > Digestive system > Liver > lobular cholestasis

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lobular cholestasis

Centrilobular cholestasis. IMG/jpg/centrilobular_cholestasis_0411_4-3.jpg IMG/jpg/centrilobular_cholestasis_0411_3.jpg IMG/jpg/centrilobular_cholestasis_0411_9.jpg IMG/jpg/pseudoacinar_formation_0411_1-2.jpg Cholestasis and apoptotic bodies IMG/jpg/liver_cholestasis_neonatal_cardiac_shock_12-4.jpg

Synopsis

- hepatocytic cholestasis

- canalicular cholestasis
- cholestaic hepatocytic rosettes
- biliary infarcts

Etiology (exemples)

- systemic sepsis (bacteriemia, septicemia)
- sickle cell anemia
- drug hepatotoxicity
- bile salt transporter mutations

- extrahepatic lymphoma
- mitochondriopathies

  • Navajo neurohepatopathy

- early large bile-duct obstruction
- post-transplant bile-flow impairment
- post transplant rejection (liver allograft rejection)
- drugs (drug-induced cholestasis)

See also

- Cholestasis

Keywords