Type of fibrohistiocytic tumors.
Variants
cellular fibrous histiocytoma
aneurysmal fibrous histiocytoma
atypical fibrous histiocytoma (pseudosarcomatous fibrous histiocytoma)
epithelioid dermatofibroma (epithelioid fibrous histiocytoma)
Immunochemistry
strong tenascin positivity at the dermal-epidermal junction overlying the lesion (100%)
tenascin within the DF lesion (80%)
CD34+ (25%) DF
Factor XIIIa+ (95%) DF
Differential diagnosis
Dermatofibroma (fibrous histiocytoma) vs DFSP (11172295)
| CD34 | 25% | 80% |
| FXIIIa | 95% | 15% |
| Tenascin in the tumor | 80% | 80% |
| Tenascin at the dermal-epidermal junction | 100% | 0% |
See also
- angiomatoid fibrous histiocytoma (specific tumoral entity)