chronic pneumonitis of infancy
Microscop
interstitial thickening
alveolar infiltrate
alveolar proteinaceous material
hyeprplasia of type II pneumocytes
Molecular biology
mutation in the surfactant protein C gene SP-C associated with familial interstitial lung disease
References
Nogee LM, Dunbar AE 3rd, Wert SE, Askin F, Hamvas A, Whitsett JA. A mutation in the surfactant protein C gene associated with familial interstitial lung disease. N Engl J Med. 2001 Feb 22 ;344(8):573-9. PMID : 11207353
Katzenstein AL, Gordon LP, Oliphant M, Swender PT. Chronic pneumonitis of infancy. A unique form of interstitial lung disease occurring in early childhood. Am J Surg Pathol. 1995 Apr;19(4):439-47. PMID: 7694945