Types
family-based designs
- transmission disequilibrium test
population-based designs
See also
expression quantitative trait loci (eQTLs)
gene expression phenotypes
genome-wide linkage analysis
genome-wide association (GWA) analysis
References
Laird NM, Lange C. Family-based designs in the age of large-scale gene-association studies. Nat Rev Genet. 2006 May;7(5):385-94. PMID: 16619052
Balding DJ. A tutorial on statistical methods for population association studies. Nat Rev Genet. 2006 Oct;7(10):781-91. PMID: 16983374
Jorgenson E, Witte JS. A gene-centric approach to genome-wide association studies. Nat Rev Genet. 2006 Nov;7(11):885-91. PMID: 17047687
Evans DM, Cardon LR. Genome-wide association: a promising start to a long race. Trends Genet. 2006 Jul;22(7):350-4. PMID: 16713652
Wang WY, Barratt BJ, Clayton DG, Todd JA. Genome-wide association studies: theoretical and practical concerns. Nat Rev Genet. 2005 Feb;6(2):109-18. PMID: 15716907
Hirschhorn JN, Daly MJ. Genome-wide association studies for common diseases and complex traits. Nat Rev Genet. 2005 Feb;6(2):95-108. PMID: 15716906