gene expression

Definition: Gene expression is the process by which the coded information of a gene is converted into the structures present and operating in the cell.

Expressed genes include those that are transcribed into mRNA and then translated into protein and those that are transcribed into RNA but not translated into protein (e.g., transfer and ribosomal RNAs).

The degree of expression is called expressivity.

Gene expression databases

 MGED Society, Microarray Gene Expression Data Society
 BodyMap at University of Tokyo
 GEO (Gene Expression Omnibus)

In humans

 HuGEIndex.org

By organs

 Kidney development gene expression database ar UCSD, the University of California at San Diego

See also

 knock-down of proteic expression

Videos

 gene expression regulation

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References

 Komili S, Silver PA. Coupling and coordination in gene expression processes: a systems biology view. Nat Rev Genet. 2008 Jan;9(1):38-48. PMID: 18071322

 Rockman MV, Kruglyak L. Genetics of global gene expression. Nat Rev Genet. 2006 Nov;7(11):862-72. PMID: 17047685

 Yanai I, Korbel JO, Boue S, McWeeney SK, Bork P, Lercher MJ. Similar gene expression profiles do not imply similar tissue functions. Trends Genet. 2006 Mar;22(3):132-8. PMID: 16480787

 Kaern M, Elston TC, Blake WJ, Collins JJ. Stochasticity in gene expression: from theories to phenotypes. Nat Rev Genet. 2005 Jun;6(6):451-64. PMID: 15883588

 Bartel DP, Chen CZ. Opinion: Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat Rev Genet. 2004 May;5(5):396-400. PMID: 15143321