Pathology
haploinsufficiency of TNXB is associated with hypermobility type of Ehlers-Danlos syndrome (MIM.130020) and Ehlers-Danlos-like syndrome (MIM.606408) (12865992)
Tenascin XB (TNXB) has been identified as a gene that is more highly expressed in malignant mesothelioma compared with ovarian/peritoneal serous carcinoma based on gene expression array analysis.
Tenascin-X may be a new diagnostic marker of malignant mesothelioma in the differential diagnosis of cancers involving the serosal cavities, particularly in the differential diagnosis between this tumor and ovarian/peritoneal serous carcinoma. (19738457)
See also
tenascins (TNs
References
Tenascin-X is a novel diagnostic marker of malignant mesothelioma. Yuan Y, Nymoen DA, Stavnes HT, Rosnes AK, Bjørang O, Wu C, Nesland JM, Davidson B. Am J Surg Pathol. 2009 Nov;33(11):1673-82. PMID: 19738457