Human pathology

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MYB

MIM.189990 6q22

V-MYB AVIAN MYELOBLASTOSIS VIRAL ONCOGENE HOMOLOG

Pathology

- MYB overexpression in colorectal cancer (CRC) is a prognostic indicator for poor survival.

References

- Hugo H, Cures A, Suraweera N, Drabsch Y, Purcell D, Mantamadiotis T, Phillips W, Dobrovic A, Zupi G, Gonda TJ, Iacopetta B, Ramsay RG. Mutations in the MYB intron I regulatory sequence increase transcription in colon cancers. Genes Chromosomes Cancer. 2006 Dec;45(12):1143-54. PMID: 16977606