MAML2
Pathology
MAML2/MECT1 (MAMl2/CRTC1) gene fusion by t(11;19)(q21;p13) in
- mucoepidermoid carcinoma (14720503)
- benign Warthin tumor (14720503)
- cutaneous clear cell hidradenoma (15729701, 17334997)
WAMTP1/MAML2 gene fusion
MLL/MAML2 gene fusion in
- secondary acute myelogenous leukemia (17551948)
- myelodysplastic syndrome with inv(11)(q21q23) (17551948)
References
Winnes M, Molne L, Suurkula M, Andren Y, Persson F, Enlund F, Stenman G. Frequent fusion of the CRTC1 and MAML2 genes in clear cell variants of cutaneous hidradenomas. Genes Chromosomes Cancer. 2007 Jun;46(6):559-63. PMID: 17334997
Tirado Y, Williams MD, Hanna EY, Kaye FJ, Batsakis JG, El-Naggar AK. CRTC1/MAML2 fusion transcript in high grade mucoepidermoid carcinomas of salivary and thyroid glands and Warthin?s tumors: implications for histogenesis and biologic behavior. Genes Chromosomes Cancer. 2007 Jul;46(7):708-15. PMID: 17437281
Nemoto N, Suzukawa K, Shimizu S, Shinagawa A, Takei N, Taki T, Hayashi Y, Kojima H, Kawakami Y, Nagasawa T. Identification of a novel fusion gene MLL-MAML2 in secondary acute myelogenous leukemia and myelodysplastic syndrome with inv(11)(q21q23). Genes Chromosomes Cancer. 2007 Jun 5; PMID: 17551948
Winnes M, Molne L, Suurkula M, Andren Y, Persson F, Enlund F, Stenman G. Frequent fusion of the CRTC1 and MAML2 genes in clear cell variants of cutaneous hidradenomas. Genes Chromosomes Cancer. 2007 Jun;46(6):559-63. PMID: 17334997
Behboudi A, Enlund F, Winnes M, Andren Y, Nordkvist A, Leivo I, Flaberg E, Szekely L, Makitie A, Grenman R, Mark J, Stenman G. Molecular classification of mucoepidermoid carcinomas-prognostic significance of the MECT1-MAML2 fusion oncogene. Genes Chromosomes Cancer. 2006 May;45(5):470-81. PMID: 16444749