Human pathology

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LSP1

MIM.153432 11p15.5

LSP1 exhibited a number of properties supporting a possible role in B-cell signaling pathways. The gene codes for a 52-kD phosphoprotein expressed only in transformed and untransformed B cells, thymocytes, and untransformed T-cell lines.

PAthology

- gene variants in predisposition to breats cancer (mammary carcinomas)