Home > A. Molecular pathology > signaling pathways
signaling pathways
Wednesday 11 June 2003
signaling network, signalling pathways, regulatory pathways, molecular pathways, signaling networks
Main signaling pathways
ALK1 pathaway
MAPK signaling pathways (ras/MAPK pathways)
- Ras/MEK/ERK signaling pathway (RAS-ERK signaling pathway)
- JNK/MAPK signaling pathway
Notch signaling pathway
WNT signaling pathway (catenins/APC signaling pathway)
PI3K/PTEN/AKT signaling pathway (phosphoinositol-3-kinase/Akt signaling pathway)
TSC/FRAP1 pathway (TSC/mTOR pathway)
NF-kappaB signaling pathway
PKA signaling pathway
SHH-GLI signaling pathway (Hedgehog-Patched signaling pathway)
TGF-beta signaling pathway
ErbB signaling pathway
receptor tyrosine kinase signaling pathways
JAKs/STATs signaling pathways
nuclear hormone signaling pathways
FANC/BRCA1/BRCA2/ATM/NBS1 signaling pathway (BRCAs signaling pathway)
Rb/E2F signaling pathway (P16(INK4A)-CDK4/6-RB pathway)
endothelin receptor signaling pathway
ARF-MDM2-P53 signaling pathway
caspases pathway
insulin signaling pathway
cytokine signaling pathways
- IL-5 signaling pathway
Databases
PID Pathway Interaction Database
KEGG pathway database
Biocarta
SPAD Signaling Pathway Database at Kyushu University
Dynamic Signaling Maps
Websites
Biosciences Pathway Central
BioPathways at Covance
Softwares
BioD, a visual language for describing, documenting and analyzing the functions of complex biological systems
PathwayAssist, software tool for analysis, expansion and visualization of biological pathways
GeneAssist Pathway Atlas
References
P-Finder: Reconstruction of Signaling Networks from Protein-Protein Interactions and GO Annotations. Young-Rae Cho, Yanan Xin, Speegle G. IEEE/ACM Trans Comput Biol Bioinform. 2015 Mar-Apr;12(2):309-21. doi : 10.1109/TCBB.2014.2355216 PMID: 26357219
Towards genome-scale signalling-network reconstructions. Hyduke DR, Palsson BO. Nat Rev Genet. 2010 Feb 23. PMID: 20177425
Bhalla US. Models of cell signaling pathways. Curr Opin Genet Dev. 2004 Aug;14(4):375-81. PMID: 15261653
Kabuyama Y, Resing KA, Ahn NG. Applying proteomics to signaling networks. Curr Opin Genet Dev. 2004 Oct;14(5):492-8. PMID: 15380239
Pires-daSilva A, Sommer RJ. The evolution of signalling pathways in animal development. Nat Rev Genet. 2003 Jan;4(1):39-49. PMID: 12509752
Tuveson DA, Fletcher JA. Signal transduction pathways in sarcoma as targets for therapeutic intervention. Curr Opin Oncol. 2001 Jul;13(4):249-55. PMID: 11429482