Human pathology

Home page > A. Molecular pathology > KIT

KIT

MIM.164920

c-kit, mast cell growth factor, MCGF, stem cell factor receptor, SCFR, CD117

Expression in tumors (Exemples)

- chromophobe renal cell carcinoma (100%)
- renal oncocytoma (100%)

Pathology

- KIT activating mutations in

Use in diagnosis

- Differential diagnosis between chromophobe renal cell carcinoma and the granular variant of clear cell renal cell carcinoma (15832088)

References

- Wang HY, Mills SE. KIT and RCC Are Useful in Distinguishing Chromophobe Renal Cell Carcinoma From the Granular Variant of Clear Cell Renal Cell Carcinoma. Am J Surg Pathol. 2005 May;29(5):640-646. PMID: 15832088