Human pathology

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Haplogroup C

Distribution

- Native Americans
- Chukchi and Siberian Eskimos

Facts

- The sequence-divergence estimates for Haplogroup A, Haplogroup C, and Haplogroup D of Siberian and Native American populations indicate that the earliest inhabitants of Beringia possessed a limited number of founding mtDNA haplotypes and that the first humans expanded into the New World approximately 34,000 years before present (YBP). (9792876)

References

- Marinho AN, Miranda NC, Braz V, Ribeiro-Dos-Santos AK, de Souza SM. Paleogenetic and taphonomic analysis of human bones from Moa, Beirada, and Ze Espinho Sambaquis, Rio de Janeiro, Brazil. Mem Inst Oswaldo Cruz. 2006 Dec 5;101 Suppl 2:15-23. PMID: 17308804

- Silva WA Jr, Bonatto SL, Holanda AJ, Ribeiro-Dos-Santos AK, Paixao BM, Goldman GH, Abe-Sandes K, Rodriguez-Delfin L, Barbosa M, Paco-Larson ML, Petzl-Erler ML, Valente V, Santos SE, Zago MA. Mitochondrial genome diversity of Native Americans supports a single early entry of founder populations into America. Am J Hum Genet. 2002 Jul;71(1):187-92. PMID: 12022039

- Bonatto SL, Salzano FM. Diversity and age of the four major mtDNA haplogroups, and their implications for the peopling of the New World. Am J Hum Genet. 1997 Dec;61(6):1413-23. PMID: 9399887