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DSG4

IMG/jpg/desmosomes_rockfeller-5-4.jpg

Desmoglein-4 (DSG4) is the main desmosome cadherin in hair follicle.

Pathology

- DSG4 is an autoantigen in pemphigus vulgaris (MIM.169610).
- mutation in the gene encoding desmoglein-4 (DSG4) causes localized autosomal recessive hypotrichosis (LAH) (MIM.607903)

Keywords