somatic mutations
constitutional mutations
Types
point mutations
in-frame mutations
-
missense mutations
- gain-of-glycosylation mutations
heteroduplexes mutations
frameshift mutations
polyglutamine mutations
protective mutations
mtDNA mutations
epimutations
synonymous mutations
mice expressing designed gene mutations
disease-predisposing mutations
dynamic mutations
Fitness effects of mutations
neutral mutations
advantageous mutations
-
protective mutations
- disease-protecting mutations
- cancer-protecting mutations
deleterious mutations
-
disease-predisposing mutations
- mutations of disease genes
- cancer-predisposing mutations
- mutations of cancer genes
- malformation-predisposing mutations
- mutations of malformation genes
See also
mutation rate
distribution of fitness effects (DFE) of mutations
References
Baer CF, Miyamoto MM, Denver DR. Mutation rate variation in multicellular eukaryotes: causes and consequences. Nat Rev Genet. 2007 Aug;8(8):619-31. PMID: 17637734