CHMPs
CHMPs is the family of chromatin-modifying protein/charged multivesicular body proteins (CHMPs).
These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs).
Some CHMPs have both nuclear and cytoplasmic/vesicular distributions. CHMP1A (MIM.164010) is required for both MVB formation and regulation of cell cycle progression