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ESCRT
Wednesday 23 May 2007
The endosomal sorting complex required for transport (ESCRT) machinery facilitates the trafficking of ubiquitylated proteins from endosomes to lysosomes via multivesicular bodies (MVBs).
A common organization of all ESCRTs is a rigid core attached to flexibly connected modules that recognize other components of the MVB pathway.
References
Williams RL, Urbe S. The emerging shape of the ESCRT machinery. Nat Rev Mol Cell Biol. 2007 May;8(5):355-68. PMID: 17450176
