BMP2
MIM.112261 20p12
Bone morphogenetic proteins BMP2 has been purified from demineralized bone on the basis of their ability to induce the formation of ectopic cartilage when implanted subcutaneously.
NB: The transforming growth factor-beta (TGFBs) superfamily encodes at least 12 members, including TGFB1 (MIM.190180), TGFB2 (MIM.190220), TGFB3 (MIM.190230), Mullerian inhibitory substance (MIF) (MIM.600957), the bone morphogenetic protein-2A (BMP2A), bone morphogenetic protein-2B (BMP2B) (MIM.112262), bone morphogenetic protein-3 (MIM.112263), and bone morphogenetic protein-6 (MIM.112266).
References
Milet J, Dehais V, Bourgain C, Jouanolle AM, Mosser A, Perrin M, Morcet J, Brissot P, David V, Deugnier Y, Mosser J. Common variants in the BMP2, BMP4, and HJV genes of the hepcidin regulation pathway modulate HFE hemochromatosis penetrance. Am J Hum Genet. 2007 Oct;81(4):799-807. PMID: 17847004