Synopsis
multiple gastric carcinoid tumors
marked hypergastrinemia
achlorhydria (lack of acid production by hypertrophic parietal cells)
multiple intramucosal and invasive carcinoid tumors of the body and fundus
marked ECL cell hyperplasia
marked hyperplasia and hypertrophy of the parietal cells
- vacuolated parietal cells
- protrusions of apical cytoplasm of the parietal cells
dilated oxyntic glands filled with inspissated eosinophilic material
Reverences
Abraham SC, Carney JA, Ooi A, Choti MA, Argani P. Achlorhydria, parietal cell hyperplasia, and multiple gastric carcinoids: a new disorder. Am J Surg Pathol. 2005 Jul;29(7):969-75. PMID: 15958864