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ADPRTL2

MIM.607725 14q11.2

Activation of ADP-ribosyltransferases (ADPRTLs), such as ADPRTL2, is an early cellular response to DNA strand breaks.

These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability.

See also

- ADPRTLs

Keywords