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ABCC11

MIM.607040 16q12.1

Pathology

- A SNP in the ABCC11 gene is the determinant of human earwax type (16444273)

- ABCC11/MRP8 confers pemetrexed resistance in lung cancer. (20718756)

- A functional ABCC11 allele is essential in the biochemical formation of human axillary odor. (19710689)

  • A SNP in the ABCC11 gene is the determinant of human earwax type. (16444273)
  • A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene. (19650936) See also

- ABCs

References

- ABCC11/MRP8 confers pemetrexed resistance in lung cancer. Uemura T, Oguri T, Ozasa H, Takakuwa O, Miyazaki M, Maeno K, Sato S, Ueda R. Cancer Sci. 2010 Jul 27. PMID: 20718756

- Yoshiura KI, Kinoshita A, Ishida T, Ninokata A, Ishikawa T, Kaname T, Bannai M, Tokunaga K, Sonoda S, Komaki R, Ihara M, Saenko VA, Alipov GK, Sekine I, Komatsu K, Takahashi H, Nakashima M, Sosonkina N, Mapendano CK, Ghadami M, Nomura M, Liang DS, Miwa N, Kim DK, Garidkhuu A, Natsume N, Ohta T, Tomita H, Kaneko A, Kikuchi M, Russomando G, Hirayama K, Ishibashi M, Takahashi A, Saitou N, Murray JC, Saito S, Nakamura Y, Niikawa N. A SNP in the ABCC11 gene is the determinant of human earwax type. Nat Genet. 2006 Jan 29; PMID: 16444273