Human pathology

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transcytosis

Function

- The apical and basolateral borders of epithelial cells are distinguished by their different protein and lipid components. The sorting of newly synthesized membrane constituents to the appropriate region of the cell is accomplished either in the trans-Golgi network or by transcytosis, the selected transport of proteins to the appropriate surface.

- Transcytosis is involved in the internalization of proteins and ligands at one surface and their transport to another.

See also

- GPI-anchored membrane proteins