Human pathology

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testicular teratoma

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Testicular dermoid cyst Testicular dermoid cyst
Teratoma of the testis

Teratomas of the testis in post-pubertal patients are histologically diverse tumors that often coexist with other types of germ cell tumors.

Types

- mature testicular teratoma
- immature testicular teratoma
- testicular teratoma component in mixed germ cell tumors

LOH study (14633619)

Chr.1 50%
Chr.2 33%
Chr.9 58%
Chr.11 43%
Chr.12 20%
Chr.18 33%

- identical allelic losses in mature teratoma and other histologic components of malignant mixed germ cell tumors of the testis (14633619)

Associations

- embryonal rhabdomyosarcoma arising in testicular teratoma of the testis (8568751, 9400455)

  • embryonal rhabdomyosarcoma arising in a testicula mature teratoma (2188021)

References

- Motzer RJ, Amsterdam A, Prieto V, Sheinfeld J, Murty VV, Mazumdar M, Bosl GJ, Chaganti RS, Reuter VE. Teratoma with malignant transformation: diverse malignant histologies arising in men with germ cell tumors. J Urol. 1998 Jan;159(1):133-8. PMID: 9400455