Human pathology

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tendon sheath fibroma

Immunochemistry:

- vimentin +
- muscle-?pecific actin +
- smooth muscle actin +
- desmin -
- CD68 +/-
- factor XIIIa +
- CD34 +

Differential diagnosis

- fibrous histiocytoma
- nodular fasciitis
- giant cell tumor of the tendon sheath
- if nuclear pleomorphism: malignant fibrous histiocytoma

Cytogenetics

- transclocation t(2;11)(q31-32;q12) (2q31-32 and 11q12)