splenic macrophagic infiltration
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diffuse histiocytosis of the spleen
Types
splenic spumous macrophagic infiltration
Etiology
metabolic diseases
- splenic storage diseases
- Gaucher disease (Gaucher cell)
- Niemann-Pick disease type 2 (NPD-2) (sea-blue histiocytes) (6184303)
disseminated atypical mycobacteriosis (6741553)
- Mycobacterium intracellulare infection (6741553)
idiopathic thrombocytopenic purpura (ITP) (ceroid histiocytes or sea-blue histiocytes) (6684881)
malignant histiocytosis (7104067)
Case records
Case 12002: Splenic spumous macrophagic infiltration in Mycobacterium avium intracellulare infection in combined immune deficiencies
Differential diagnosis
splenic inflammatory pseudotumor (18040148)
See also
- ceroid histiocytes or sea-blue histiocytes
References
Yamadori I, Motoi M, Hayashi K, Tsutsumi A, Ogawa K, Doi K, Hamaya K. Disseminated atypical mycobacteriosis. Acta Pathol Jpn. 1984 Mar;34(2):459-69.PMID: 6741553