spindle assembly checkpoint
SAC
The spindle assembly checkpoint (SAC) ensures the fidelity of chromosome segregation by preventing cell-cycle progression until all the chromosomes make proper bipolar attachments to the mitotic spindle and come under tension.
See also
mitosis
References
Musacchio A, Salmon ED. The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol. 2007 May;8(5):379-93. PMID: 17426725