Human pathology

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spinal paraganglioma

spinal cord paraganglioma

Spinal cord paragangliomas are uncommon. More than 120 CNS paragangliomas have been documented, and are most frequently found in the region of the cauda equine and filum terminale, although they have also been reported in the thoracic and cervical regions.

In a study of 30 spinal paraganglioma cases by Moran et al, 19 were located in the lumbar region, 6 in the cauda equina, 2 in the filum terminale, 2 in the thoracic region, and 1 in the cervical region. In another study, 30 of 31 tumors originated in the cauda equina, and 25 of these arose from the filum.

Although cauda equina paragangliomas are categorized as a WHO grade 1, and are usually well-demarcated, encapsulated, and slow-growing, locally invasive and recurrent tumors have been reported.

case reports

- UPSM 523

See also

- paragangliomas

References

- Stowinski J, Stomal M, Bierzynksa-Macyszyn, Swider K. Paraganglioma of the lumbar spinal canal - case report. Folia Neuropathologica 2005;43:119-122.

- Moran CA, Rush W, Mena H. Primary spinal paragangliomas: a clinicopathological and immunohistochemical study of 30 cases. Histopathology 1997;31:167-173.

- Matschke J, Westphal M, Lamszus K. Intradural mass of the cauda equina in a woman in her early 60s. Brain Pathology 2005;15:169-170.

- Sonneland PRL, Scheithauer BW, LeChago J, Crawford BG, Onofrio BM. Paraganglioma of the cauda equina region: clinicopathologic study of 31 cases with special reference to immunocytology and ultrastructure. Cancer 1986;58:1720-1735.

- Walsh JC, O?Brien DF, Rawluk KD. Paraganglioma of the cauda equina: a case report and literature review. Surgeon 2005;April:113-116.

- Pigott TJ, Lowe JSL, Morrell K, Kerslake RW. Paraganglioma of the cauda equina. J Neurosurg 1990;73:455-458.

- Sundgren P, Annertz M, Englund E, Stromblad LG, Holtas S. Paragangliomas of the spinal canal. Neuroradiology 1999;41:788-794. Ashkenazi E, Onesti ST, Kadar A, Llena JF. Paraganglioma of the filum terminale: case report and literature review. J Spinal Disorders 1998;11:540-542.