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papillary renal cell carcinoma

MIM.605074

Morphological classification

- adult papillary renal tumor with oncocytic cells (16327429)
- adult papillary renal tumor with basophilic cells
- pediatric papillary renal tumor (TFE3- or TFEB-associated)

Molecular classification

- MET-associated papillary renal cell carcinoma
- TFE3-associated papillary renal cell carcinoma
- T7/T17-associated papillary renal cell carcinoma

Etiology

- germline mutations of the gene MET
- somatic mutations of the gene MET
- TFE3 rearrangements

References

- Lefevre M, Couturier J, Sibony M, Bazille C, Boyer K, Callard P, Vieillefond A, Allory Y. Adult papillary renal tumor with oncocytic cells: clinicopathologic, immunohistochemical, and cytogenetic features of 10 cases. Am J Surg Pathol. 2005 Dec;29(12):1576-81. PMID: 16327429

- Dharmawardana PG, Giubellino A, Bottaro DP. Hereditary papillary renal carcinoma type I. Curr Mol Med. 2004 Dec;4(8):855-68. PMID: 15579033

Keywords